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October 29, 2004 (Friday):
Noon-5:00 pm Registration and assignment to Panel Discussion Groups 1, 2 or 3.
Coordinators: Kathy Lau and Janet Ireland
5:00-6:30 pm Session I: Welcome to Michigan State University and keynote address
Chairs: Dr. Mark Mirando (USDA-CSREES), Dr. Lou DePaolo (NICHD)
5:00-5:30 pm Welcome - Dr. Lou Anna K. Simon,
Provost and President-Designate, Michigan State University
5:30-6:30 pm Keynote address
Are the Domestic Farm Species Redundant as Models in Biomedical
Research? Does Mighty Mouse Rule Supreme? Dr. R. Michael
Roberts University of Missouri
6:30-7:30 pm Cash bar and hors d'oeuvres
7:30-9:00 pm Dinner
Welcome to Michigan State University, Dr. Jeffrey Armstrong, Dean, College
of Agriculture and Natural Resources, MSU
October 30, 2004 (Saturday):
6:30-8:00 am Continental breakfast
8:00-10:00 am Session II: Reproductive Physiology & Developmental Biology
Chairs: Dr. Debora Hamernik (USDA-CSREES) and Dr. Lou DePaolo (NICHD)
Speakers:
Prenatal programming of reproductive and metabolic dysfunction: the
sheep as a model; Dr. Vasantha, University of Michigan
The Chicken - A valuable model for investigations in reproductive biology
and reproductive diseases; Dr. Janice, University of Illinois
Swine as biomedical models; Dr. Randy, University of Missouri
10:00-10:15 am Break and refreshments
10:15-12:15 pm Session III: Health and Disease:
Chairs: Dr. Bradley Fenwick, Vice President for Research, Virginia Polytechnic
Institute and University and Dr. John Baker, Interim Director, Agricultural
Experiment Station, Michigan State University
Speakers:
Use of cattle to study the immunobiology of γδ T cells; Dr. Mark Jutila, Montana
State University
Understanding pathogen transmission in emerging infectious disease; Dr. Guy
Palmer, Washington State University
Porcine models in the study of cardiovascular effects of exercise in health and
disease; Dr. Harold Laughlin, University of Missouri
12:15–1:00 pm Lunch
1:00-3:00 pm Session IV: Advanced Technology and Genomics
Chairs: Dr. Daniel Schmoldt, USDA-CSREES, and Dr. Paul Coussens,
Michigan State University
Speakers:
Microbial pathogenomics; Dr. Vivek Kapur, University of Minnesota
New approaches to the prevention of sudden cardiac death; validation in
canine and porcine models; Dr. Robert Gilmour, Jr., Cornell University
Nuclear transfer cloning of cattle: a model system for studying the genomic
biology of totipotent stem cells; Dr Harris Lewin, University of Illinois
3:00-3:15 pm Break and refreshments
3:15–5:15 pm Session V: Nutrition: Moderators: Dr. Etta Saltos (USDACSREES) and Dr. Pam
Starke-Reed (NIH, DNRC)
Speakers:
The pig and sheep as animal models for nutrition research; Dr. Guyao Wu,
Texas A&M University
Nutritional biochemistry of the developing neonate: Insights gleaned from a
piglet model; Dr. Jack Odle, North Carolina State University
Pre- and post-natal influences on adipose tissue development and metabolism:
the pig as a model; Dr. Dorothy Hausman, University of Georgia, Athens
5:30-7:00 pm Dinner
7:00–9:00 pm Multiple Breakout Sessions I:
Moderators:
Group 1 – Dr Debora Hamernik (USDA)
Group 2 – Dr. Fuller Bazer (Texas A &M)
Group 3 – Dr. Louis DePaolo (NICHD)
Questions to address:
• What are the important research areas in human health not identified by
speakers that could be advanced by use of domestic species as biomedical
models?
• Are there any real or perceived “barriers” using domestic species as models
for biomedical research?
• In what ways will the new knowledge generated during the genomics era of
research in digestive, reproductive, immune, and other systems benefit both
animal agriculture and human medicine?
• Is justification for use of domestic animals as models for biomedical research
more difficult compared with rodent models? If so, why?
9:00-11:00 pm Social and cash bar
October 31, 2004 (Sunday):
6:30-8:00 am Continental breakfast
8:00-10:00 am Multiple Breakout Sessions II:
Moderators:
Group 1 – Dr Debora Hamernik (USDA)
Group 2 – Dr. Fuller Bazer (Texas A&M)
Group 3 – Dr. Louis DePaolo (NICHD)
Questions to address:
• What is needed to enhance the use of domestic species as biomedical
models? For example, in the current funding systems, what processes should
be kept, discarded, or created to enhance the use of domestic animals as
biomedical models? What would the future look like if the use of domestic
species for biomedical research were not enhanced?
• What is the desired (and realistic) outcome/expectation for the use of domestic
animals as biomedical models? What are the major constraints/barriers to
achieving these goals?
• Should strategies to address the issues raised in Question 1 (Breakout
Session II) be developed, and if they are developed, such as in a “white paper”,
what is the likelihood that they will enhance use of domestic species as
biomedical models by 2010? Who will develop and implement these
strategies?
• How could greater cooperation between medical schools and animal science
departments to use domestic species as biomedical models be fostered?
10:00-10:30 am Break and refreshments
10:30–12:30 pm Final Workshop Summary and Planning Session.
Chairs: Dr. Michael Roberts, University of Missouri; Dr. Bradley Fenwick, Virginia
Polytechnic Institute and State University
Moderators from each group will present summary of results of Breakout
Sessions I and II
Open for any questions/issues
12:30 pm Adjourn